Rabia Akram (2014-VA-769)
Assessment Of Glycemic Modulation In Diabetic Sprague Dawley Rats Through Feeding Camel Milk Whey - 2016. - 42p.;
The number of people diagnosed with diabetes is increasing tremendously exhausting the ability of health care systems to deal with the epidemic. Therefore it is necessary to find scientific merits in traditional folk remedies to justify their claims. Number of investigational studies on the traditional belief that regular consumption of camel milk helps in the prevention and control of diabetes are done by experimentations on different animal models have given significant results. Therefore present project was designed for evaluation of camel milk whey as functional food against diabetes mellitus. In the first part of study whey was extracted and in the second part of study efficacy of camel milk whey as functional food against diabetes mellitus was evaluated in male Sprague dawley rats. Seventy two rats were induced diabetes by injecting Streptozotocin (50 mg/ kg) dissolved in cold 10mM of citrate buffer at pH of 4.5. Diabetes was induced in group I, II and III rats and feed on three types of diet (standard diet + water, standard diet + raw camel milk and standard diet + camel milk whey) respectively. After the induction of diabetes it was confirmed by checking the 8 hour fastening blood glucose level using the Abbot glucometer, rats with blood glucose greater than 200mg/dl were considered diabetic. Base line reading were recorded by decapitating 6 rats from each group. Parameters which were consider included serum blood glucose level(mg/dl), TGL (mg/dl), cholesterol (mg/dl), HDL (mg/dl) and LDL (mg/dl) further more to observe the changes at cellular level histopathology of liver and pancreas was also performed. Therefore the present study consisting of duration of 6 weeks showed that camel milk whey is concentrated with number of beneficial proteins that are helpful in reducing the blood glucose level significantly in diabetic rats as well as it also remarkably in creased the level of LDL. The histopathology report of organs i.e. liver and pancreas showed improvement gradually with the ongoing treatment and these improvements strongly prove
Summary
38
that composition of serum not only improved temporarily but long term use of camel milk whey could not only help to improve serum composition but it also cases regeneration of degraded cells of pancreas and also improved the sinusoidal congestion in liver.
Food And Nutrition
2773-T
Assessment Of Glycemic Modulation In Diabetic Sprague Dawley Rats Through Feeding Camel Milk Whey - 2016. - 42p.;
The number of people diagnosed with diabetes is increasing tremendously exhausting the ability of health care systems to deal with the epidemic. Therefore it is necessary to find scientific merits in traditional folk remedies to justify their claims. Number of investigational studies on the traditional belief that regular consumption of camel milk helps in the prevention and control of diabetes are done by experimentations on different animal models have given significant results. Therefore present project was designed for evaluation of camel milk whey as functional food against diabetes mellitus. In the first part of study whey was extracted and in the second part of study efficacy of camel milk whey as functional food against diabetes mellitus was evaluated in male Sprague dawley rats. Seventy two rats were induced diabetes by injecting Streptozotocin (50 mg/ kg) dissolved in cold 10mM of citrate buffer at pH of 4.5. Diabetes was induced in group I, II and III rats and feed on three types of diet (standard diet + water, standard diet + raw camel milk and standard diet + camel milk whey) respectively. After the induction of diabetes it was confirmed by checking the 8 hour fastening blood glucose level using the Abbot glucometer, rats with blood glucose greater than 200mg/dl were considered diabetic. Base line reading were recorded by decapitating 6 rats from each group. Parameters which were consider included serum blood glucose level(mg/dl), TGL (mg/dl), cholesterol (mg/dl), HDL (mg/dl) and LDL (mg/dl) further more to observe the changes at cellular level histopathology of liver and pancreas was also performed. Therefore the present study consisting of duration of 6 weeks showed that camel milk whey is concentrated with number of beneficial proteins that are helpful in reducing the blood glucose level significantly in diabetic rats as well as it also remarkably in creased the level of LDL. The histopathology report of organs i.e. liver and pancreas showed improvement gradually with the ongoing treatment and these improvements strongly prove
Summary
38
that composition of serum not only improved temporarily but long term use of camel milk whey could not only help to improve serum composition but it also cases regeneration of degraded cells of pancreas and also improved the sinusoidal congestion in liver.
Food And Nutrition
2773-T