Effect Of Different Routes Of Vaccination Against Newcastle Disease On Lymphoid Organs Of Broilers (Record no. 2509)

000 -LEADER
fixed length control field 01994nam a2200205Ia 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20150921133632.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 150525s2002 xx 000 0 und d
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title eng
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 0774,T
100 ## - MAIN ENTRY--AUTHOR NAME
Personal name Rabia Salam
110 ## - MAIN ENTRY--CORPORATE NAME
Location of meeting Dr. Asim Aslam
245 ## - TITLE STATEMENT
Title Effect Of Different Routes Of Vaccination Against Newcastle Disease On Lymphoid Organs Of Broilers
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Year of publication 2002
502 ## - DISSERTATION NOTE
Dissertation note This project was designed to compare two routes (intraocular and drinking water) of vaccination against Newcastle disease in terms of protection against velogenic field isolate of NDV by noting immune response and morphological changes in Harderian gland, Bursa of Fabricius and thymus of broilers. This project would also help to evaluate role of Harderian gland to generate local and humoral immunity in response to eye drop and drinking water vaccination against NDV.
For this purpose, a total of 160 day-old chicks were procured from local commercial hatchery. At day 7 birds were randomly divided into four groups i.e. A, B, C, D comprising 40 birds each. Group A and B were vaccinated through ocular and oral route respectively. While groups C and D were kept as control. At day 21, groups A and B were revaccinated through the same routes. At day 28, groups A, B and C were further sub-divided into two subgroups each i.e. Al and A2, Bi and B2, Cl and C2, respectively. Subgroups Al, Bl and Cl were challenged, ocularly while subgroups A2, B2 and C2 were challenged orally with velogenic field isolate of NDV.

Ocular vaccination resulted in higher level of circulating antibodies and increased number of plasma cells in Harderian gland. It can be inferred that ocular vaccination stimulated Harderian gland to produce strong lcal protective immunity both in ocular and oral mucosa.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical Term Department of Pathology
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Dr. Khalid
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Dr. Shakil Akhtar Khan
710 ## - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element Faculty of Veterinary Sciences
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Thesis
Holdings
Damaged status Collection code Permanent Location Current Location Shelving location Date acquired Full call number Accession Number Koha item type
  Veterinary Science UVAS Library UVAS Library Thesis Section 2015-05-28 0774,T 0774,T Thesis


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