Bioavailability Of Norfloxacin After Flock Medication Via Drinking Water In Broilers (Record no. 2616)
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| fixed length control field | 02568nam a2200205Ia 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20150921152625.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150525s2004 xx 000 0 und d |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 0889,T |
| 100 ## - MAIN ENTRY--AUTHOR NAME | |
| Personal name | Irfan Obaid Ullah |
| 110 ## - MAIN ENTRY--CORPORATE NAME | |
| Location of meeting | Dr.Muhammad Ovais Omer |
| 245 ## - TITLE STATEMENT | |
| Title | Bioavailability Of Norfloxacin After Flock Medication Via Drinking Water In Broilers |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Year of publication | 2004 |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | This project was done to determine the plasma concentration of Norfioxacin in broiler chickens after its administration through drinking water, stability of Norfioxacin in drinking water and to check the bioavailability of two products of Norfioxacin of two different companies by using the technique of microbiological assay. In this project collected 60 birds which were divided into two groups which were further divided into six sub-groups containing 5 birds each. Two different Norfioxacin products (Norexcel given to group A and Anflox to group B) was used at the dose rate of lml/1 through drinking water and then blood samples were taken at different specific time intervals to determine the plasma concentration of Norfioxacin through microbiological assay technique. The Maximum plasma concentration (Cpmax) attained by group A was 2.700±0.0683µg/ml and group B was 2.583±0.083µg/ml. The Maximum time (Tmax) for both group A and B was 2 hours. Area under the curve for group A was 201.166 ± 3.387µg/hr/ml and for group B was 203.616 ± 2. 674µg/hr/ml and Cpmjn. for group A was 1.150±0.0428 µg/ml and for group B was 1.016±O.0401µg/ml. This project showed that Oral administration of Norfioxacin, gave better bio-availability than other routes of administration of drug. Maximum plasma concentration (Cpmax) achieved by Norfioxacin in this study is enough to check the sensitive micro-organism. The medication of Norfioxacin through drinking water is better because it remains stable in water, and its stability in water is upto 90% which checked after every 4 hours, so no suggestions for renewal of fresh solution of Norfioxacin. According to this data we concluded that the dose given in this project (1m1/l) of drinking water is enough for the treatment and cure of the bacteriological infection and this also tells that the way of medication through continuous drinking water is the method of choice for getting maximum results. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical Term | Department of Physiology |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dr. Muhammad |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dr. Muhammad Ashraf |
| 710 ## - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | Faculty of Biosciences |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Thesis |
| Damaged status | Collection code | Permanent Location | Current Location | Shelving location | Date acquired | Full call number | Accession Number | Koha item type |
|---|---|---|---|---|---|---|---|---|
| Veterinary Science | UVAS Library | UVAS Library | Thesis Section | 2015-05-28 | 0889,T | 0889,T | Thesis |