Effects Of Infectious Bursal Desease Vaccine And Vaccination Schedule In Imunity Induceds By Newcastle Disease (Record no. 2739)
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| fixed length control field | 02768nam a2200205Ia 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20150930143152.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150525s2008 xx 000 0 und d |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 1017,T |
| 100 ## - MAIN ENTRY--AUTHOR NAME | |
| Personal name | Kashif-ur-Rehman |
| 110 ## - MAIN ENTRY--CORPORATE NAME | |
| Location of meeting | Prof.Dr.Mansur-ud-Din Ahmad |
| 245 ## - TITLE STATEMENT | |
| Title | Effects Of Infectious Bursal Desease Vaccine And Vaccination Schedule In Imunity Induceds By Newcastle Disease |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Year of publication | 2008 |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | The study was carried out for verifying the interference of infectious bursal disease vaccines conmonly used in Pakistan on the immunity to Newcastle disease vaccines. Infectious bursal disease (IBD) is a viral disease producing suppression in humoral immune response causing degeneration of bursa of Fabricius. Different vaccines are available in the market for mass scale immunization of chickens. The study was carried out to compare the immunosuppressive effects of intermediate strain, hot strain and complex IBDV vaccines on immunity induced by NDV vaccine. Vaccine efficacy was studied by measuring the induced humoral antibody level using HI (Haemagglutination inhibition) test for NDV and indirect ELISA (enzyme-linked immunosorbent assay) (Kirkegaard' & Perry Laboratories - KPL) to detect antibodies against IBDV. The parameters used to evaluate the effects of IBDV vaccine on broiler chicks were immune response to NDV vaccination, weight of lymphoid organs such as bursa of Fabricius, thymus and spleen, post virulent NDV challenge and FCR. The results showed that IBDV vaccinated groups A, B, C, D and E had lower HI antibody profile, higher bursa, spleen and thymus body weight ratio, poor FCR and higher post challenge mortality than NDV vaccinated group F. The HI serum antibody profile revealed that the groups vaccinated with IBDV hot strain had significantly lower antibody titer as compared to the intermediate strain of IBDV vaccinated birds. In addition to that hot strain vaccine found to be more damaging to the bursa, spleen and thymus than the intermediate strain vaccine. The hot strain had adverse effects on the feed conversion ratio of birds as well. The challenge with virulent NDV revealed that IBDV vaccine treated groups were overall higher mortality than the only NDV vaccinated chickens. The study suggested the use of intermediate strain as vaccine since it had least interference with the antibody production against ND. However, hot strain used in this study had adversely affected the NDV HI. titer and caused more damage to the lymphoid organs and reduced feed conversion ratio (FCR). |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical Term | Department of Microbiology |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dr.Imran Najeeb |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Prof.Dr.Azhar Maqbool |
| 710 ## - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | Faculty of Veterinary Sciences |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Thesis |
| Damaged status | Collection code | Permanent Location | Current Location | Shelving location | Date acquired | Full call number | Accession Number | Koha item type |
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| Veterinary Science | UVAS Library | UVAS Library | Thesis Section | 2015-05-27 | 1017,T | 1017,T | Thesis |