Receptor Binding Techniques
By: Davenport, Anthony
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Contributor(s): Davenport, Anthony P.
Material type: 
BookSeries: Publisher: New Jersey: Humana Press, 2005Edition: 2nd ed.Description: 240 p.ISBN: 158829420X (hardcover); 9781588294203 (hardcover).Subject(s): Cell receptors--Research | Radioligand assay | Ligand binding (Biochemistry) | GeneticsDDC classification: 571.6 Davenport 18848 2nd 2005 Genetics Summary: A comprehensive collection of readily reproducible methods for studying receptors in silico, in vitro, and in vivo. These cutting-edge techniques cover mining from curated databases, identifying novel receptors by high throughput screening, molecular methods to identify mRNA encoding receptors, radioligand binding assays and their analysis, quantitative autoradiography, and imaging receptors by positron emission tomography (PET). Highlights include phenotypic characterization of receptors in knockout mice, imaging receptors using green fluorescent protein and fluorescent resonance energy transfer, and quantitative analysis of receptor mRNA by TaqMan PCR. These book equips the researcher with techniques for exploring the unprecedented number of new receptor systems now emerging and the so-called "orphan" receptors whose activating ligand has not been identified.
| Item type | Current location | Collection | Call number | Status | Date due | Barcode | Item holds |
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Books
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UVAS Library Genetics | Veterinary Science | 571.6 Davenport 18848 2nd 2005 Genetics (Browse shelf) | Available | 18848 |
Browsing UVAS Library Shelves , Shelving location: Genetics , Collection code: Veterinary Science Close shelf browser
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A comprehensive collection of readily reproducible methods for studying receptors in silico, in vitro, and in vivo. These cutting-edge techniques cover mining from curated databases, identifying novel receptors by high throughput screening, molecular methods to identify mRNA encoding receptors, radioligand binding assays and their analysis, quantitative autoradiography, and imaging receptors by positron emission tomography (PET). Highlights include phenotypic characterization of receptors in knockout mice, imaging receptors using green fluorescent protein and fluorescent resonance energy transfer, and quantitative analysis of receptor mRNA by TaqMan PCR. These book equips the researcher with techniques for exploring the unprecedented number of new receptor systems now emerging and the so-called "orphan" receptors whose activating ligand has not been identified.
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