Comparative Efficacy Of Infectious Bursal Disease Vaccines In Broiler Chickens
By: Tahir Waheed Khan
| Dr. Muhammad Amin Sheikh.
Contributor(s): Dr. Khushi Muhammad | Dr. Muhammad | Faculty of Veterinary Sciences.
Material type: 
BookPublisher: 1995Subject(s): Department of MicrobiologyDDC classification: 0419,T Dissertation note: The present study was carried out to know the comparative efficacy of different IBD vaccines including Rhone Merleux, Solvay, TAD and CVS in broiler chickens. The evaluation was based on the immune response developed against the vaccine concerned and its assessment through agar gel precipitation test (AGPT) and indirect haemagglutination (IHA) test.
All the birds prior to their vaccination were examined for the presence of passive immunity, both through AGPT and IHA. AGPT could only detect 60-80% birds for maternal immunity, whereas IHA showed the presence of this immunity in all the experimental birds.
All the vaccinated groups were examined for their immune response on 7th, 14th and 21st day post-vaccination. Both AGPT and H-IA showed the decline in immunity on 7th day post-vaccination and then a gradual increase in titres occurred at 14th day of vaccination. The titres attained their peak on 21st day post-vaccination.
With AGPT on 21st day post-vaccination the birds for various vaccines gave precipitin lines respectively as 76, 89, 93 and 100 per cent, for Rhone Merieux, Solvay,TAD and CVS vaccines.
With IHA the highest titres obtained on 21st day post- vaccination was 1:128 for each vaccine, however, the number of birds giving this titre varied being only one bird for Rhone Merleux, Solvay , TAD and 3 birds from CVS. Nevertheless, the next best titre obtained was 1:64 and the number of birds giving this titre was 2, Nil, 2 and 8 birds from Rhone Merieux, Solvay, TAD and CVS. The predominant number of birds, vaccinated against each vaccine developed a titre of 1:16 observed at 14th day and 21st day post- vaccination.
The challenge infection results showed that birds with lilA titres of upto 1:4 developed severe lesions on their bursae, and other parts of the body, alongwith giving less BBR values. In this way the better IHA titre gave protection to the birds against a challenge infection.
All the four vaccines gave identical results for their efficacy against the IBDV infection, however, CVS vaccinated birds developed highest titres in greater number.
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Thesis
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UVAS Library Thesis Section | Veterinary Science | 0419,T (Browse shelf) | Available | 0419,T |
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The present study was carried out to know the comparative efficacy of different IBD vaccines including Rhone Merleux, Solvay, TAD and CVS in broiler chickens. The evaluation was based on the immune response developed against the vaccine concerned and its assessment through agar gel precipitation test (AGPT) and indirect haemagglutination (IHA) test.
All the birds prior to their vaccination were examined for the presence of passive immunity, both through AGPT and IHA. AGPT could only detect 60-80% birds for maternal immunity, whereas IHA showed the presence of this immunity in all the experimental birds.
All the vaccinated groups were examined for their immune response on 7th, 14th and 21st day post-vaccination. Both AGPT and H-IA showed the decline in immunity on 7th day post-vaccination and then a gradual increase in titres occurred at 14th day of vaccination. The titres attained their peak on 21st day post-vaccination.
With AGPT on 21st day post-vaccination the birds for various vaccines gave precipitin lines respectively as 76, 89, 93 and 100 per cent, for Rhone Merieux, Solvay,TAD and CVS vaccines.
With IHA the highest titres obtained on 21st day post- vaccination was 1:128 for each vaccine, however, the number of birds giving this titre varied being only one bird for Rhone Merleux, Solvay , TAD and 3 birds from CVS. Nevertheless, the next best titre obtained was 1:64 and the number of birds giving this titre was 2, Nil, 2 and 8 birds from Rhone Merieux, Solvay, TAD and CVS. The predominant number of birds, vaccinated against each vaccine developed a titre of 1:16 observed at 14th day and 21st day post- vaccination.
The challenge infection results showed that birds with lilA titres of upto 1:4 developed severe lesions on their bursae, and other parts of the body, alongwith giving less BBR values. In this way the better IHA titre gave protection to the birds against a challenge infection.
All the four vaccines gave identical results for their efficacy against the IBDV infection, however, CVS vaccinated birds developed highest titres in greater number.
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