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Chemotherapeutic Studies On Experimentally Induced Ascaridia Galli Infection In Broilers

By: Basir Ahmed | Dr.Muhammad Sarwar Khan.
Contributor(s): Dr.Iftikhar Gul Ahmad | Dr.Shakil | Faculty of Veterinary Sciences.
Material type: materialTypeLabelBookPublisher: 2000Subject(s): Department of Clinical Medicine & SurgeryDDC classification: 0685,T Dissertation note: The study was conducted to assess the effectiveness of albendazole and oxfendazole. It was found that abendazole at dose rate of 10 mg / kg bodyweight (once orally) was 87.87% effective and oxfendazole at dose rate of 7.5 mg / kg bodyweight (once orally) was 90.90% effective against Ascaridia gjjJ infection. Parasite effected the live weight of birds and thymus weight significantly. Similarly, the total serum protein level, serum glucose and haemaglobin level were reduced significantly in infected groups as compared with group A (control non infected). The infected groups C & D were treated with albendazole and oxfendazole respectively, although treatment had reduced the number of worms but the live bodyweight, thymus weight, total serum protein, serum glucose and haemoglobin values were not significantly increased in five days post treatment as compared with group B (control infected). The GMHI titre (Geomatric Mean Haemagglutination Inhibition Titre) against Newcastle disease vaccine was much low in infected groups (B, C and D), than control non-infected group (A). The GMHI titre in medicated groups (C&D) having some improvement of GMHI titre than control infected (B) in five days, but comparatively much low than group A. The development in poultry improvement is possible if there is anthelmentic treatment which not only increases the bodyweight of the bird, but also help in better immune response against different diseases of the bird. It is suggested that sub clinical I un observed parasitic infection should be checked with oxfendazole and albendazole treatment and particularly the layers type of birds should be dewormed at an interval of 90 days at least.
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The study was conducted to assess the effectiveness of albendazole and oxfendazole. It was found that abendazole at dose rate of 10 mg / kg bodyweight (once orally) was 87.87% effective and oxfendazole at dose rate of 7.5 mg / kg bodyweight (once orally) was 90.90% effective against Ascaridia gjjJ infection. Parasite effected the live weight of birds and thymus weight significantly. Similarly, the total serum protein level, serum glucose and haemaglobin level were reduced significantly in infected groups as compared with group A (control non infected). The infected groups C & D were treated with albendazole and oxfendazole respectively, although treatment had reduced the number of worms but the live bodyweight, thymus weight, total serum protein, serum glucose and haemoglobin values were not significantly increased in five days post treatment as compared with group B (control infected).
The GMHI titre (Geomatric Mean Haemagglutination Inhibition Titre) against Newcastle disease vaccine was much low in infected groups (B, C and D), than control non-infected group (A). The GMHI titre in medicated groups (C&D) having some improvement of GMHI titre than control infected (B) in five days, but comparatively much low than group A.

The development in poultry improvement is possible if there is anthelmentic treatment which not only increases the bodyweight of the bird, but also help in better immune response against different diseases of the bird. It is suggested that sub clinical I un observed parasitic infection should be checked with oxfendazole and albendazole treatment and particularly the layers type of birds should be dewormed at an interval of 90 days at least.

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