The study was conducted to determine the effect of commercially available "Norponin 200 Liquid" on urcase activity and development of ascites in broilers. The active ingredient in the product is saponins. Norponin 200 Liquid was mixed in water and offered to broiler chickens. Two commercial broiler rations were prepared. One was broiler starter ration containing 28 10 K cal/kg metabolizable energy and 20 % crude protein. Second was broiler finisher ration with 2900 K cal/kg metabolizable energy and 18.50 % crude protein. Chicks were divided into four groups i.e. A, B, C and D, respectively. Bach group offered different concentrations of Norponin 200 Liquid. Group A acted as control group. There was no mixing of Norponin 200 Liquid in it. Group B was offered 2.5 ml Norponin 200 Liquid/100 liter of drinking water. Group C was offered 5.0 ml of Norponin 200 Liquid/100 liter of drinking water. Group D was offered 7.5 ml of Norponin 200 Liquid) 100 ml of drinking water. Feed and water was offered ad libitum to the chicks. A total of 240 day-old-broiler hubbred chicks were purchased from a local commercial hatchery and were randomly divided into 4 groups having 60 birds in each group. Each group was further subdivided into 6 replicates comprising 10 birds each. Initial body weight was recorded on day first just after the arrival of chicks in brooding room. The body weight, feed consumption and feed conversion ratio were recorded at the end of each week. Urease activity, mortality percentage and economic study of medicine used were determined at the end of experiment. The experiment was completed in 6 weeks. The results of feed consumption indicated that birds fed on same starter and Finisher rations but with different concentrations of Norponin 200 Liquid to different groups i.e. A, B, C and D in drinking water from 0-6 Weeks of age were 3847, 3813, 3831 and 3827 grams, respectively. Rcs.ults showed that birds of group A consumed more feed as compared to other groups.

The weight gain of birds in different groups i.e. A, B, C and D from 0-6 weeks were 1741, 1809, 1857 and 1895 grams, respectively. Results showed that birds in group D gained maximum weight i.e. 1895 grams per bird. The feed conversion ratio from 0-6 weeks of age were 2.20, 2.10, 2.05 and 2.01, respectively. Results showed that better feed conversion ratio was observed in group D, which as offered maximum concentration of Norponin 200 Liquid in drinking water i.e. 7.50 ml/l00 liter of drinking water. Mortality due to ascites was observed only in groups A and B, respectively. In group A, it was 8 % and in group B it was 5 %, respectively.

Urease activity was also observed in all four groups and it was recorded that maximum urease activity was observed in group A (acted as control) and minimum urcase activity was observed in group D (offered maximum concentration of Yucca sapoin)

CONCLUSION:- It was concluded that Norponin 200 Liquid offered at 7.50 ml/100
liter of drinking water gives comparatively bctter results than 2.5 ml! 100 liter, 5.0 ml! 100 liter of drinking water and control groups.