Detection And Control Of Vaccination Stress Following Vaccination With Inactivated Virus Newcastle Disease
By: Kanwar Muhammad Naeem
| Dr. Shakil Akhtar Khan.
Contributor(s): Dr.Javed Rashid | Dr.Khushi Muhammady | Faculty of Veterinary Sciences.
Material type: 
BookPublisher: 1997Subject(s): Department of PathologyDDC classification: 0807,T Dissertation note: This study was intended to detect and control of the vaccination stress following vaccination with inactivated virus Newcastle disease vaccine intramuscularly (i/rn) and its effects on immune response in commercial broiler chicks. One hundred and forty day-old broiler chicks were divided into four groups i.e. A, 13, C and D having 35 birds each. Chicks from group A were kept as control. Group B was given vaccine and no treatment. Group C was given vaccine and probiotic (protexin). Group 0 was given vaccine and vitamins (Vitaoligosol). Seven birds of each group were slaughtered on 1st, 2nd, 3rd and 4th day post vaccination and remaining 7 birds of each group were slaughtered on day 45th, for collection of blood samples. The blood samples from 7 randomly selected birds were collected on day 16th, 30th and 45th for determination of antibody titre. The following parameters were studied: (i) determination of heterophil/lymphocyte ratio (ii) estimation of antibody response against Newcastle disease vaccine (iii) estimation of serum biochemica' substances (iv) determination of adrenal gland body weight index and (v) pathological study of adrenal glands. Inactivated virus vaccine against Newcastle disease induced transient stress in broiler chicks and detection of serum biochemical substances (protein, glucose and cholesterol) can act good indicators for detection of vaccination stress. Protexin and vitaoligosol played minor role in combating vaccination stress in this study.
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Thesis
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UVAS Library Thesis Section | Veterinary Science | 0807,T (Browse shelf) | Available | 0807,T |
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This study was intended to detect and control of the vaccination stress following vaccination with inactivated virus Newcastle disease vaccine intramuscularly (i/rn) and its effects on immune response in commercial broiler chicks. One hundred and forty day-old broiler chicks were divided into four groups i.e. A, 13, C and D having 35 birds each. Chicks from group A were kept as control. Group B was given vaccine and no treatment. Group C was given vaccine and probiotic (protexin). Group 0 was given vaccine and vitamins (Vitaoligosol). Seven birds of each group were slaughtered on 1st, 2nd, 3rd and 4th day post vaccination and remaining 7 birds of each group were slaughtered on day 45th, for collection of blood samples. The blood samples from 7 randomly selected birds were collected on day 16th, 30th and 45th for determination of antibody titre. The following parameters were studied: (i) determination of heterophil/lymphocyte ratio (ii) estimation of antibody response against Newcastle disease vaccine (iii) estimation of serum biochemica' substances (iv) determination of adrenal gland body weight index and (v) pathological study of adrenal glands. Inactivated virus vaccine against Newcastle disease induced transient stress in broiler chicks and detection of serum biochemical substances (protein, glucose and cholesterol) can act good indicators for detection of vaccination stress. Protexin and vitaoligosol played minor role in combating vaccination stress in this study.
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