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Epidemiological Trends, Clinical Profile And Risk Factors Associated With Crimean Congo Hemorrhagic Fever In Quetta, Balochistan

By: Khushal Khan Kasi | Prof. Dr. Muhammad Athar Khan.
Contributor(s): Prof. Dr. Mansur-ud-Din Ahmad.
Material type: materialTypeLabelBookPublisher: 2012Subject(s): Department of Epidemiology & Public HealthDDC classification: 1377,T Dissertation note: Crimean congo hemorrhagic fever (CCHF) is an important disease in suburbs of Quetta in particular, and other cities of Balochistan in general. The cases of this disease are brought to the public hospital for treatment purposes. The study was carried out to understand the descriptive nature of the disease with respect to geographic, temporal and personal distribution. The second part of study comprised of cross sectional as well as case-control study for the identification of different risk factors in patients as compared to their control admitted in the same hospitals. The highest numbers of CCHF cases were from Quetta i.e. 35, 82 cases were male and 19 cases of female, small scale sheep and goat farmer has highest number of cases i.e, 59. Mean age for male patients was 30.82±15.47 years, while for female patients mean age was 29.17±16.40 years with a p-value= 0.685. Mean platelet count for male and female patients was 450n.29±35934.14 and 35388.89±18081.96 respectively with a p-value= 0.270. Mean Hemogobin level for male and female patients was 11.52±2.78 and 9.80±3.23 respectively, and with a p-value=O.023. Among the patients, 5 patients were positive for IgG and IgM antibodies, 9 patients were having A+ blood group, 44 with B+, 16 with 0+, 1 with AB+ and 29 was not reported, 21 patients died and the remaining patients discharged, and the highest number of cases were between April and September. A significant association exist between platelet count with respect to cases who suffered from CCHF (p-value= 0.000), male were 1.157 times more prone to CCHF as compared to female (OR=1.157), (p-value=0.629) and (CI=0.641-2.089), and animals at home have has more susceptibility to CCHF cases (OR=3.538), (p-value=O.OOO) and (CI=2.219-5.642).
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Crimean congo hemorrhagic fever (CCHF) is an important disease in suburbs of Quetta in
particular, and other cities of Balochistan in general. The cases of this disease are brought to the
public hospital for treatment purposes. The study was carried out to understand the descriptive
nature of the disease with respect to geographic, temporal and personal distribution. The second
part of study comprised of cross sectional as well as case-control study for the identification of
different risk factors in patients as compared to their control admitted in the same hospitals. The
highest numbers of CCHF cases were from Quetta i.e. 35, 82 cases were male and 19 cases of
female, small scale sheep and goat farmer has highest number of cases i.e, 59. Mean age for male
patients was 30.82±15.47 years, while for female patients mean age was 29.17±16.40 years with
a p-value= 0.685. Mean platelet count for male and female patients was 450n.29±35934.14 and
35388.89±18081.96 respectively with a p-value= 0.270. Mean Hemogobin level for male and
female patients was 11.52±2.78 and 9.80±3.23 respectively, and with a p-value=O.023. Among
the patients, 5 patients were positive for IgG and IgM antibodies, 9 patients were having A+
blood group, 44 with B+, 16 with 0+, 1 with AB+ and 29 was not reported, 21 patients died and
the remaining patients discharged, and the highest number of cases were between April and
September. A significant association exist between platelet count with respect to cases who
suffered from CCHF (p-value= 0.000), male were 1.157 times more prone to CCHF as compared
to female (OR=1.157), (p-value=0.629) and (CI=0.641-2.089), and animals at home have has
more susceptibility to CCHF cases (OR=3.538), (p-value=O.OOO) and (CI=2.219-5.642).

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