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1. Prevalence And Chemotherapy Of Coccidiosis In Sheep And Goats And Its Effect On Certain Blood Parameters

by Nasir Ali, Faridi | Dr. Muhammad Sarwar Khan | Dr. Khalid Pervaz | Dr. Mubasher | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1995Dissertation note: This project was designed to find out the prevalance and chemotherapy of coccidiosis in sheep and goats and its effect on certain blood parameters like Haemoglobin, TLC, DLC, Glucose,and Total Serum Protein. Two drugs namely suiphadimidine and suiphaqunoxaline were used in this research project. For this purpose 60 animals(i.e sheep and goats) were taken and divided into 3 groups(A,B and C) containing 20 animals each(i.e 10 sheep and 10 goats). Group A was again subdivided into two subgroups Ag & As containing 10 animals each(i.e 10 goats and 10 sheeps) were treated with sulphadimidine.Group B was again subdivided into two subgroups Bg & Bs containing 10 animals each(i.e 10 goats and 10 sheeps) were treated with suiphaquinoxaline. Group C was again subdivided into two subgroups Cg & Cs containing 10 animals each (i.e 10 goats and 10 sheeps) were kept as infected non.medicated control. The efficacy of drugs were determined on the reduction of OPG in faeces. From the results it is find out that the average OPG on zero day of medication in groups i.e Ag,As & Bg,Bs were 75100, 72200, 60800 & 67200 respectively.The average reduction of OPG on 10th day of medication in groups i.e Ag,As & Bg,Bs were 300,340,120 & 280 respectively.The OPG of control groups were increased on the subsequent days. The average Haemoglobin on zero day of medication in groups Ag,As,& Bg,Bs were 6.53,8.02,6. 89 & 7.93 respectively The average Haemoglobin on lOtti day of medication in groups Ag,As,Bg,Ss were 8.628.80, 9.44 & 8.78 respectively.The Haemglobin of the control groups were decreased on subsequent days. Average TLC on zero day of medication in groups Ag,As,Bg,Bs were 16.50 ,16.50 & 15.50,19.50.Average TLC on 10th day of medication in groups Ag,As & Bg,Bs were 14.50,12.90 & 13.60,13.50 respectively.The TLC of control groups were increased on the subsequent days.Average DLC on zero day of medication in groups Ag was 49.40,68.00,7.00 11.10 & 17.50 in group Bg was 51.20 ,70.30,6.90, 12.20 & 19.40 in group As was 50.20,70.20,8.00,12.00 & 18.50 in group Bs was 50.40.71.60,6.10,17.20 & 18.40 .Average DLC on 10th day of medication in groups Ag was 48.40,67.00,7.00 11.10 & 17.50 in group Bg was 50.20 ,69.30,7.10,12.20 & 19.40.ln Group As was 49.40,69.10,8.00,12.00 & 18.50 in group Bs was 49.40,70.60,6.10,17.20,18.40.DLC of the control groups were incresed on the subsequent days. Average Blood Glucose on zero day of medication in groups Ag,As,Bg,Bs were 24.30, 31.30 & 29.30, 35.50 respectively.Average Blood Glucose on 10th day of medication in groups Ag,As,Bg,Bs were 37.00, 42.40, 42.80, 45.00. Blood glucose in control were decreased on the subsequent days. Average Total Serum protein on zero day of medication in groups Ag,As & Bg,Bs were 3.52,4.25,3.93,4.18. Average Total Serum protein on 10 th day of medication in groups Ag,As,Bg,Bs were 4.89,5.56 & 5.43,5.57 respectively.The total serum protein in control groups were decreased on the susequent days. Availability: Items available for loan: UVAS Library [Call number: 0426,T] (1).

2. A Study Of Changes In Blood Electrolytes And Pcv In Equine Colic

by Mazhar Ayaz, M | Dr. Khalid Pervaz | Dr. Muhammad Sarwar Khan | Dr. Shakil | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1995Dissertation note: Besides mechanized transportation horses have still global importance not only for the communication but it is thought as symbol of superiority in many countries of the world. Horses are confronted with colic once in their life span that some times results in uncompareable loss to the owner. Only a timely and accurate diagnosis is the beacon of hope to save the life. To study the effects of colic on PCV and Blood Electrolytes, twenty horses suffering from colic were taken into investigation to asses the site and type of colic, while ten normal horses were kept as control. Diseased horses were divided into three groups A, B & C mild, moderate and severe respectively. Physical signs of group A were of mild nature comprising swishing of the tail, looking at the flank and lying down for the short periods, while group B showed moderate pain like lying down but not violently and increased bouts of pain. Animals in group C exhibited signs of severe pain by showing severe depression, restlessness, patchy sweating, struggling violently and kicking at the belly due to sharp continuous pain. The heart rate, respiration and rectal temperature in all groups was increased. Rectal palpation was performed in all groups to determine the site of the disease. Changes found in blood electrolytes like Na+, K+, C1- and HCO3 were measured by flame photometry. Group A, B and C showed decrease in Na+, and HCO3 concentration in serum while concentration of K and C1 in serum were normal in all groups. PCV was measured by Wintrobe micro-haematocrit method in all groups. Group A and C showed normal PCV but it was lower in group B. These all observations showed that the animals of group A were suffering from impaction of ileacaecal valve. Pain was not so severe nature that may cause death in colic cases while the animals in group B were showing signs of spasmodic colic. The abnormalities were not so severe to threat the life of the animal but were elevated than the normal. Group C was considerably serious that might lead to death if unattended because the variations and findings were similar with obstruction of small intestine. The serum electrolytes in this group were increased than the other two groups alongwith the elevated respiration, heart rate and rectal temperature that were helping in assessing the condition of the animal. PCV was the reliable tool to know the degree of dehydration in the severe cases. Rectal palpation helped in differentiating the various segments of the intestines involved and the severity of the disease in the diseased animals. Availability: Items available for loan: UVAS Library [Call number: 0472,T] (1).

3. Comparative Efficacy Of Three Newly Introduced Drugs For The Control Of Experimentally Induced Coccidiosis In Broiler Chicks

by Aslam, M | Dr. M. Sarwar Khan | dr. Kamran | Dr. Khalid Pervaz | Faculty of Veterinary Sciences.

Material type: book Book; Format: print ; Literary form: not fiction Publisher: 1998Dissertation note: One hundred and fifty brioler chicks reared under standars and managmental conditions, were divided into five groups A, B, C, D and E each comprising 30 birds at the ag of 21 days. From 22nd day to onward group A, B and C were given feed mixed with coccidiostats i.e. diclazuril (200mg/kg of feed), maduramicin ammonium 500mg/kg of feed) and salinomycin (1gm/kg of feed) respectively till the end of experiment while group D and E were fed with usual feed. On 28th day, the group A, B, C and D were infected with 75000, sporulated occyst/bird while gropu E was non-infected non-medicated control. Clinical signs were observed only in group B, C and D. The total oocyst count in all groups on zero day of infection was zero. On 1st, 4th and 8th day after the appearance of clinical symptoms, the total oocyst count in group A, B, C and D were 2500, 4900, 9700 and 209600 respectively, while group E examined nil being control non-infected group. Morbidity observed in group B, C and D was 3.33% 16.66% and 83.33% respectively while in group A and E morbidity was not observed. Mortality was observed only in groups C and D that was 3.33% and 30% respectively. The feed intake and feed conversion ratio of group A, B and C was almost equal, while of group D (infected and non-medicated) is concerned it showed better result. Postmortem examination revealed severe enteritis an hemorrhagic lesions in small intestines and caeca, while on histopathology, damage to the absorptive tissue and destructions of the intestinal villi alongwith the merozoites, schizonts and gametocytes in the mucosa and sub-mucosal region of intestine and caeca were observed. The study showed the prophylactic efficacy of diclazuril, maduramicin ammonium and salinomycin in descending ordre respectively. Diclazuril was to be the drug of choic against coccidiosis. Availability: Items available for loan: UVAS Library [Call number: 0561,T] (1).

4. Prevalence And Chemotherapy Of Cestode Infection In Wild Felidae

by Zahid Zia | Dr. Khalid Pervaz | Dr. M. Akram | Dr. M. Sarwar Khan | Faculty of Veterinary Sciences.

Material type: book Book; Format: print Publisher: 1998Dissertation note: The present wok was conducted to see the efficacy of Niclosamide (Yomesan), Mebendazole (Vermox) and Praziquantel (Droncit) against cestode infection in wild felids in captivity because zoological gardens are permanent source of parastic infestation A survey was conduced to estimate ethe prevalence of various specises of cestodes in 40 wild fields kept in Lahore Zoo and Luch Irani Circus. The prevalence rate was recorded for Lahore Zoo 42.86% and for Lucky Irani Circus 100%. Overall prevalence was estimated (60%). The prevalence rate of Dipylidium caninum, Echinococcus/Taenia species, Spriometra felis and Joyeuxiella pasaquaeli was recroded 32.60, 55.33, 39.81 and 27.90 percent, respectively. The animals showing moderat to heavy infection were selected for therapeutic trails. Two trainls were conducted wild felids kept in the Lahore Zoo and Luch Irani Circus comprising 12 animals each. In both experimental station four groups i.e. A, B, C and D of animals were made. Group A, B and C wre treated with Niclosamide (Yomesan)Mebendazole (Vermox) and Praziquantle (Droncit) respectively, while group D was kept as untreated control group. The efficacy of the drug was detrmined on the basis of reduction in the number of ova and segments discharged in the faeces on 7th, 14th, 21st and 28th day of post medication. Results revealed that Praziquantel (Droncit) was the drug of choice against all species of cestodes, as it was found highly effective throughout the experiment. Membendazole (Vermox) was also found 100% effective against different species of cestodes upto 14th day of the experiment. Niclosamide (Yomesan) was not found as effective as other two drugs. Availability: Items available for loan: UVAS Library [Call number: 0567,T] (1).



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