000			02477nam a2200193Ia 4500
005			20151005152628.0
008			150525s2010xx 000 0 und d
041			_aeng
082			_a1397,T
100			_aIjaz Alvi _97987
110			_cProf.Dr.Muhammad Ashraf _94840
245			_aEvaluation Of Empirical Therapy In Escherichia Coli Induced Acute And Uncomplicated Urinary Tract Infection
260			_c2010
502			_aThe acute and uncomplicated urinary tract infection is one of the common diseases of human genitourinary tract, most com~only caused by E.coli, and study in patients suffering from acute and uncomplicated urinary tract infection was conducted in one hundred in tertiary care Mayo hospital Lahore. The urine samples from patients were collected after the diagnosis and were analyzed for its causative/pathogenic organism. Out of 100 urine samples the Escherichia coli was found as the most common cause of uUTI (acute and uncomplicated urinary tract infection) (61 %),Jollowed by Pseudomonas aeruginosa (15%), Klebsiella pneumoniae (11 %), Staphylococcus aureus (7%),Proteus mirabilis (6%), The urinary tract infections were found most frequent in female (59.9%) than male (40.1 %). Only Escherichia coli isolated strains of bacteria were subjected to antibiogram against nine commonly used antibiotics (Ciprofloxacin, Norfloxacin, Pipemedic acid, , Co-arnoxiclave, Co-trimoxazole, Amikacin, Ceftriaxone, Imipenurn, and Meropenum) for evaluation of bacterial resistance and antibiotic sensitivity, the comparative analysis showed that among the nine (09) antibiotics used the E. coli strains prevalent in Punjab especially to the patients at Mayo hospital were maximally resistant to norfloxacin 63.93% (flouroquinolone), followed by ciprofloxacin 57.37 %, Co-trimoxazole 40.98, Co- amoxiclave 39.34 %, Pipemedic acid 36.06 %, Ceftriaxone 32.78 %, Amikacin 27.88 %, meropenum 8.20 % and imipenum found only 4.92 % resistant to E. coli strains. It was concluded that irnipenurn was found to be most sensitive with 86.88 % followed by meropenum 77.05%, Amikacin 63.96 %, Ceftriaxone 57.38, co-amoxiclave 57.37 %, co-trimoxazole 42.63 %, pipemedic acid 31.16 %, ciprofloxacin 24.59 % and norfloxacin was found to be the least s e n si t i v e drug to E.coli prevalent in Punjab.
650			_aDepartment of Pharmaoclogy & Toxicology _95037
700			_aDr. Aftab _96259
700			_aDr. Muhammad Ovais Omer _95891
942			_cTH
999			_c3106 _d3106